TheMedEmpire Podcast
Evidence-based discussions
Trusted, evidence-based discussions with world-leading experts delivering to you accurate reliable health information in an era of widespread misinformation.
TheMedEmpire Podcast
Trusted, evidence-based discussions with world-leading experts focused on cardiometabolic health, disease prevention, and longevity, delivering accurate and trusted health information in an era of widespread misinformation. This podcast is for both doctors and the public.
Doctors will hear and learn directly from world-leading experts themselves. These experts are the ones who write clinical guidelines and lead world-changing research, allowing doctors and medical students to gain firsthand access to their knowledge, experience, research, and clinical perspectives.
The public benefits by receiving health information from trusted sources, helping raise health awareness and empower individuals to take charge of their health.
Dr. Paul Whelton is one of the world’s most influential living authorities in hypertension. His work has helped shape how high blood pressure is understood, defined, prevented, and treated worldwide. He led some of the most important blood pressure trials in modern medicine, including the landmark SPRINT trial, as well as ALLHAT, TOHP, and TONE. He also chaired the 2017 ACC/AHA Hypertension Guideline, which redefined hypertension at 130/80 mmHg and marked a major shift toward earlier prevention and intervention. A former President of the World Hypertension League, Dr. Whelton has published more than 700 peer-reviewed scientific papers and has held major leadership roles across cardiovascular medicine, nephrology, epidemiology, and public health.
Watch on YouTubeDr. Giuseppe Mancia is the former President of the European Society of Hypertension and the Former President of the International Society of Hypertension, and currently serves as President of the Foundation of the European Society of Hypertension. Dr. Mancia is among the most highly cited researchers in hypertension, renowned for his landmark work on blood pressure regulation, autonomic control, and the clinical relevance of white-coat hypertension. As a lead author of multiple European hypertension guidelines, he has been instrumental in shaping contemporary global standards for hypertension diagnosis, risk stratification, and cardiovascular prevention.
Watch on YouTubeDr. Richard Johnson is one of the most highly accomplished nephrologists and researchers in metabolic health. He is the highest cited researcher on fructose metabolism and its impact on metabolic health, kidney disease, and hypertension. His pioneering work has reshaped our understanding of how sugar, uric acid, and diet drive obesity, diabetes, and cardiovascular disease. He is also the founding editor of the leading textbook Clinical Nephrolog, with over 83,000 citations
Watch on YouTubeHypertension Masterclass: The Ultimate Guide to High Blood Pressure, Explained by the World’s Leading Global Authorities. Four of the most respected names in medicine share their insights on hypertension — a combination of the very best minds, brought together from prior interviews with four of the world’s most respected experts in one video.
Watch on YouTubeDr. Robert Lustig is one of the most prominent and influential voices in modern metabolic health, known worldwide for challenging conventional thinking around sugar, insulin resistance, obesity, and chronic metabolic disease. A pediatric endocrinologist, researcher, and Professor Emeritus at the University of California, San Francisco, Dr. Lustig has spent decades studying the hormonal and metabolic drivers of disease. His work has had a major impact on how both doctors and the public think about sugar, ultra-processed food, obesity, insulin resistance, and the prevention of metabolic disease. Through his research, books, lectures, and public education, he has become one of the leading international advocates for improving metabolic health and addressing the root causes of chronic disease.
Watch on YouTubeThree of the most respected experts in hypertension share their insights on exercise-induced hypertension—one of the most overlooked issues in cardiology, sports cardiology, and hypertension.
Watch on YouTubeDr. Ralph DeFronzo is the greatest living diabetologist and the father of insulin resistance. He invented the SGLT2 inhibitor class of drugs, which benefits millions of people around the world, and brought metformin to the United States single-handedly. His work and research have revolutionized our understanding of insulin resistance, from his discovery of the “Ominous Octet” and now the “Noxious Nine,” which remains one of the most impactful conceptual frameworks in diabetes pathophysiology. His work and research continue today, as he pushes the field of diabetology forward through his work on hypercortisolism, insulin resistance, beta-cell regeneration, and the search for therapies that could ultimately transform—and potentially cure—both type 1 and type 2 diabetes.
Watch on YouTubeDr. Robert Lustig is one of the most influential physician-scientists in global metabolic health. A former UCSF professor, internationally highly cited researcher, and bestselling author of Fat Chance and Metabolical, his work fundamentally changed how medicine and public health understand obesity, insulin resistance, and the role of sugar and ultra-processed foods. His research and policy advocacy have shaped clinical practice, nutritional guidelines, and global metabolic-disease prevention strategies.
Watch on YouTubeDr. Ralph DeFronzo is one of the world’s most influential figures in diabetes research, whose work revolutionized our understanding of insulin resistance and beta-cell dysfunction. He brought metformin to the United States and invented the SGLT2 class of medications, transforming the therapeutic landscape for type 2 diabetes, heart failure, and kidney disease. His introduction of the “Ominous Octet” remains one of the most impactful conceptual frameworks in diabetes pathophysiology, fundamentally reshaping clinical research, education, and treatment strategies worldwide. He has received numerous prestigious awards for Mentorship, honoring both his scientific leadership and his profound influence on generations of clinician-scientists.
Watch on YouTubeDr. Eric C. Westman, MD, MHS, Dip. ABOM, is one of the world’s most influential physicians in the clinical use of low-carbohydrate and ketogenic nutrition for managing diabetes and obesity, and a pioneering authority in Internal Medicine and Obesity Medicine. He is the co-founder and Director of one of the first academic clinics in the United States dedicated to therapeutic carbohydrate restriction—Duke’s groundbreaking Keto Medicine Clinic—established in 2006 following nearly a decade of clinical research on low-carbohydrate and ketogenic diets.
Watch on YouTubeIn this episode, we explore the fundamentals of sugar, fructose, and carbohydrates—breaking down the essential concepts everyone needs to understand.. Three of the most respected names in medicine share their insights on What is Sugar — a combination brought together from prior interviews with three of the world’s most respected experts.
Watch on YouTubeDr. Thomas Dayspring, MD, FACP, FNLA, is a world-renowned expert in lipidology and cardiovascular prevention and one of the most respected and influential voices in the field. With over 40 years of clinical and academic experience, he has delivered more than 4,000 lectures globally and authored over 50 scientific publications. He has received multiple prestigious honors, including the National Lipid Association President’s Service Award in 2011 and the NLA Clinician/Educator Award in 2023. Dr. Dayspring is widely regarded as a leading authority on lipoprotein metabolism, atherothrombosis, and advanced cardiovascular risk assessment, and is renowned for translating highly complex lipid science into practical clinical strategies. His work has had a profound influence on how cardiovascular risk is understood, assessed, and managed in preventive medicine.
Watch on YouTubeDr. Paul D. Thompson, MD, is a Past President of the American College of Sports Medicine and one of the world’s leading cardiologists and most influential authorities in sports cardiology, exercise medicine, and preventive cardiology. He is Chief of Cardiology Emeritus at Hartford Hospital, Professor of Medicine Emeritus at the University of Connecticut, and founder of Hartford Hospital’s Athlete’s Heart Program. Dr. Thompson has been at the forefront of research on exercise, cardiovascular disease, sudden cardiac events in athletes, lipid metabolism, and statin-associated muscle symptoms, helping shape modern understanding of both the cardiovascular benefits and potential risks of exercise.
Watch on YouTubeDr. Thomas Dayspring, MD, FACP, FNLA, is a world-renowned expert in lipidology and cardiovascular prevention. With over 40 years of clinical and academic experience, he has delivered 4,000+ lectures globally and authored over 50 scientific publications. He has received multiple prestigious awards, including the NLA President’s Service Award (2011) and the NLA Clinician/Educator Award (2023). Dr. Dayspring is widely regarded as a leading authority on lipoprotein metabolism, atherothrombosis, and advanced cardiovascular risk assessment, and is known for translating complex lipid science into practical strategies for clinicians. His work has had a profound impact on how cardiovascular risk is evaluated and managed in preventive medicine.
Watch on YouTubeDr. Anna Lembke is one of the world’s leading authorities in addiction medicine. She is Professor of Psychiatry and Chief of Addiction Medicine at Stanford University School of Medicine, and an internationally recognized clinician-scientist whose work has reshaped modern understanding of addiction, dopamine regulation, and compulsive behaviors. Her research, clinical leadership, and bestselling book Dopamine Nation have influenced psychiatric practice, neuroscience, and public discourse on addiction worldwide.
Watch on YouTubeDr. Georgia Ede is a Harvard-trained, board-certified psychiatrist and a global authority on the role of nutrition in mental health. She was the first psychiatrist at both Harvard University Health Services and Smith College to introduce nutrition-based treatment strategies into mainstream psychiatric care. Dr. Ede co-authored the first inpatient clinical study of the ketogenic diet for serious mental illness and created the first medically accredited training program dedicated to ketogenic therapies in psychiatry. Her pioneering work has helped establish metabolic and nutritional psychiatry as an emerging approach to understanding and treating mental illness.
Watch on YouTubeDr. David J. Linden, PhD, is a world-renowned neuroscientist and Professor of Neuroscience at the Johns Hopkins University School of Medicine. A leading authority on brain function and neuroplasticity, his research has explored the cellular mechanisms of memory, addiction, brain injury, sensory processing, and the neural basis of pleasure and behavior. He has authored or co-authored more than 100 peer-reviewed scientific publications and served for many years as Editor-in-Chief of the prestigious Journal of Neurophysiology. Dr. Linden is also an acclaimed science communicator and bestselling author of several influential books, including The Compass of Pleasure, Touch, and The Accidental Mind, helping bring some of the most complex discoveries in modern neuroscience to a global audience.
Watch on YouTubeDr. Anna Lembke is one of the world’s leading authorities in addiction medicine. She is Professor of Psychiatry and Chief of Addiction Medicine at Stanford University School of Medicine, and an internationally recognized clinician-scientist whose work has reshaped modern understanding of addiction, dopamine regulation, and compulsive behaviors. Her research, clinical leadership, and bestselling book Dopamine Nation have influenced psychiatric practice, neuroscience, and public discourse on addiction worldwide.
Watch on YouTubeDr. Stephen P. Hinshaw led one of the largest and most influential long-term studies of girls with ADHD, transforming scientific understanding of how ADHD affects females across childhood, adolescence, and adulthood. He is one of the world’s leading psychologists and a globally recognized authority on ADHD and developmental psychopathology, serving as Distinguished Professor of Psychology at UC Berkeley and Professor Emeritus of Psychiatry and Behavioral Sciences at UCSF. His pioneering research, books, and advocacy have had a major impact on psychiatry, psychology, behavioral science, and mental health worldwide.
Watch on YouTubeDr. Robert Lustig is one of the most influential physician-scientists in global metabolic health. He is also a leading neuroendocrinologist and neuroscientist with decades of experience studying how the brain, hormones, and metabolism interact. His work has explored reward pathways, addiction, stress, depression, and metabolic health, including how modern food and lifestyle can “hijack” the brain’s reward system — themes he developed in The Hacking of the American Mind and and is developing in his upcoming book Freeing the Hostage Brain.
Watch on YouTubeد. فارس استشاري في الطب الباطني، يمتلك أكثر من 10 سنوات من الخبرة في مجال أمراض القلب الوقائية والصحة القلبية الأيضية. أجرى شخصياً أكثر من 15,000 اختبار جهد قلبي في مستشفيات رائدة، ولديه خبرة واسعة في تقييم عوامل الخطورة القلبية والأمراض الأيضية مثل السكري، ارتفاع الكوليسترول، وارتفاع ضغط الدم، كما شارك في نقاشات علمية متقدمة مع خبراء عالميين في مجالات الوقاية القلبية والصحة الأيضية. في هذا الفيديو يقدم طرحاً علمياً متكاملاً ومترابطاً للجلطة القلبية، يبدأ بتوضيح كونها السبب الأول للوفاة عالمياً، ثم يشرح آلية حدوثها داخل الشرايين ولماذا هي نتيجة تراكم طويل لعوامل الخطورة وليست حدثاً مفاجئاً. كما يستعرض بشكل منهجي دور الأمراض الأيضية مثل مقاومة الإنسولين والسكري وارتفاع الضغط والكوليسترول، وتأثير نمط الحياة من الغذاء والرياضة والتدخين، مع توضيح أهمية التحاليل الدورية في الكشف المبكر عن الخطر. ويختتم برسالة وقائية عملية قائمة على الأدلة تركز على منع المرض قبل حدوثه وليس فقط علاجه بعد وقوعه
Watch on YouTubeد. صهيب الراضي استشاري الطب الباطني وأمراض الغدد الصماء مع تخصص دقيق في أورام الغدد الصماء، ويعمل حالياً في مستشفيات رائدة، وتدرّب في مؤسسات أكاديمية مرموقة منها جامعة تورنتو وجامعة ماكغيل في كندا. في هذا اللقاء يقدّم شرحاً طبياً متكاملاً حول السمنة من منظور هرموني واستقلابي، موضحاً آلية عمل حقن إنقاص الوزن ومتى تُستخدم ومن هو المرشح المناسب لها. كما يناقش اضطرابات الغدة الدرقية وتأثيرها على الوزن والطاقة، وإدارة الدهون والكوليسترول وعلاقتها بخطر القلب، إضافة إلى السكري ومقاومة الإنسولين، مع استعراض بعض التحاليل المخبرية الروتينية وتصحيح العديد من المفاهيم الشائعة، وتقديم خطوات عملية مبنية على الأدلة لتحسين الصحة الأيضية على المدى الطويل. والكوليسترول، وتشخيص وعلاج السكري، مع توضيح المفاهيم الشائعة والخطوات العملية المبنية على الأدلة.
Watch on YouTubeDr. David J. Linden, PhD, is a world-renowned neuroscientist and Professor of Neuroscience at the Johns Hopkins University School of Medicine. A leading authority on brain function and neuroplasticity, his research has explored the cellular mechanisms of memory,
Watch on YouTubeIn this video, we bring together three of the world’s leading brain health experts to explain neuroplasticity and its role in mental illness: Dr. Anna Lembke (Stanford psychiatrist and Chief of Addiction Medicine), Dr. Mark D'Esposito (Distinguished Professor of Neuroscience at UC Berkeley), and Dr. David Linden (Johns Hopkins leading Neurobiologist).
Watch on YouTubeDr. Mark D'Esposito, M.D., a neurologist and leading professor of neuroscience and psychology at the University of California, Berkeley. He has over 430 research publications cited over 80,000 times, has written and edited seven books, and has received numerous competitive NIH and private foundation research grants. He has trained over 80 graduate students and post-doctoral fellows. He served as President of the Society for Behavioral and Cognitive Neurology, Chairman of the International Society for Human Brain Mapping, and the Editor-In-Chief of the Journal of Cognitive Neuroscience. He was elected to the American Association for the Advancement of Science and the American Academy of Art & Sciences, and received the Fred Kavli Distinguished Career Contributions Award from the Cognitive Neuroscience Society.
Watch on YouTubeDr. Emeran Mayer is a world-renowned gastroenterologist, neuroscientist, and Professor in Medicine, Physiology, and Psychiatry at the University of California, Los Angeles (UCLA). He is internationally recognized as one of the foremost experts on the brain–gut connection. For decades, Dr. Mayer has pioneered research on how the mind, brain, and gut microbiome interact to shape both physical and mental health. He is the Founding Director of the UCLA Brain Gut Microbiome Center and has authored more than 400 scientific papers. In addition, he is the bestselling author of The Mind-Gut Connection and The Gut-Immune Connection, books that have brought his groundbreaking insights to a global audience. By integrating gastroenterology and neuroscience, Dr. Mayer has become a leading authority on how diet, stress, and emotions influence the gut—and how the gut, in turn, impacts mood, immunity, and overall well-being.
Watch on YouTubeDr. Antonio C. Bianco is one of the world’s foremost authorities on thyroid hormone physiology and hypothyroidism. A former President of the American Thyroid Association and Professor of Medicine and Endocrinology, he has published hundreds of scientific papers and played a major role in shaping modern understanding of thyroid hormone metabolism and hypothyroidism treatment. He is also the author of the influential book Rethinking Hypothyroidism and one of the leading voices challenging and advancing how thyroid disease is understood and treated.
Watch on YouTubeDr. Andrew W. Campbell is a Professor of Immunology and Toxicology and the world’s leading authority on mold- and mycotoxin-related illness. With over 35 years of experience, he has treated more than 20,000 patients worldwide and authored over 100 peer-reviewed publications and textbook chapters. He has lectured at Oxford, Harvard, and Johns Hopkins and remains a leading figure in environmental medicine and immunotoxicology.
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